Innate Viral Receptor Signaling Determines Type 1 Diabetes Onset
نویسندگان
چکیده
منابع مشابه
Innate Viral Receptor Signaling Determines Type 1 Diabetes Onset
Heritable susceptibility of the autoimmune disorder, type 1 diabetes (T1D), only partially equates for the incidence of the disease. Significant evidence attributes several environmental stressors, such as vitamin D deficiency, gut microbiome, dietary antigens, and most notably virus infections in triggering the onset of T1D in these genetically susceptible individuals. Extensive epidemiologica...
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Qpe 1 diabetes is a disease characterized by progressive loss of p-cell function due to an autoimmune reaction affecting the islets of Langerhans. It is now generally accepted that cytokines are implicated in the pathogenesis of autoimmune diseases. Animal studies have shown that interleukin-1 p, tumor necrosis factora, and interferon-y affect type 1 diabetes development profoundly. I t has bee...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2017
ISSN: 1664-2392
DOI: 10.3389/fendo.2017.00249